I tried this supplement after reading the review last year. It's fantastic! I purchased my dog from a breeder of champion AST thinking I would get a genetically superior dog. Wrong. Her radius in her L leg is about 1/4 inch shorter that normal. My orthopedic vet told me she would always limp with any exercise, not to let her run and not to get her another dog to play with because it would be too hard on her joint.
We tried Liquid Health Gluco, Chron, and MSM. We noticed results in 6 weeks. She no longer limps and we got her a playmate too. I have not seen her limp since being on this supplement. We took her to the beach a few months ago and still no signs of limping with extreme exercise. I love this stuff!